SCHEMBL2465787

SCHEMBL2465787

[c]1c(COc2ccccc2)cccc1COc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.52
KCNA3 P22001 1/20 0.46
APP P05067 1/20 0.45
MAOB P27338 5/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGS2 P35354 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RECQL P46063 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2303318 0.81 APP (0.50) APPMAOBRAB9ASMN1; SMN2NPC1
SCHEMBL2306843 0.79 IDH1 (0.47) KCNH2KCNA3APPMAOBRAB9A
SCHEMBL2302051 0.78 KCNA3 (0.54) KCNH2KCNA3RAB9ASMN1; SMN2NPC1
SCHEMBL2454046 0.78 KCNH2 (0.46) KCNH2KCNA3APPMAOBRAB9A
SCHEMBL2302475 0.75 NR4A2 (0.41) KCNH2KCNA3APPMAOBRAB9A
SCHEMBL850999 0.70 APP (0.78) APPMAOBRAB9ASMN1; SMN2LMNA
Benzylphenylether SCHEMBL61660 0.70 LMNA (0.74) APPMAOBRAB9ASMN1; SMN2LMNA
SCHEMBL931875 0.70 PTPRC (0.59) KCNH2KCNA3APPMAOBRAB9A
SCHEMBL1548932 0.70 F10 (0.62) APPMAOBRAB9ASMN1; SMN2LMNA
Benzylphenylether SCHEMBL23235842 0.69 LMNA (0.71) APPMAOBRAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023190912-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 日本ポリケム株式会社 2023-10-05 WO disclosed
EP-3978537-B1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER UNIV TOKYO (JP) 2023-09-13 EP disclosed
CN-113874402-B Polar group-containing olefin copolymer 国立大学法人东京大学 2023-04-04 CN disclosed
WO-2023033030-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 国立大学法人 東京大学 2023-03-09 WO disclosed
EP-3208285-B2 PRODUCTION METHOD OF AN ETHYLENE AND/OR ALPHA-OLEFIN-BASED IONOMER JAPAN POLYETHYLENE CORP (JP) 2023-01-25 EP disclosed
US-20220220239-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER THE UNIVERSITY OF TOKYO (JP) 2022-07-14 US disclosed
CN-113874402-A Polar group-containing olefin copolymer 国立大学法人东京大学 2021-12-31 CN disclosed
WO-2020241715-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER 国立大学法人東京大学 2020-12-03 WO disclosed
US-10717855-B2 Production method of ethylene-based ionomer and ethylene-based ionomer JAPAN POLYETHYLENE CORPORATION (JP) 2020-07-21 US disclosed
EP-3208285-B1 PRODUCTION METHOD OF AN ETHYLENE AND/OR ALPHA-OLEFIN-BASED IONOMER JAPAN POLYETHYLENE CORP (JP) 2020-02-05 EP disclosed
EP-3173430-A1 OLEFIN POLYMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN POLYMER Japan Polyethylene Corporation (JP) 2017-05-31 EP disclosed
CN-106573998-A Olefin polymerization catalyst and process for producing olefin polymer 日本聚乙烯株式会社 2017-04-19 CN disclosed
US-20170002120-A1 PROCESS FOR PRODUCING ETHYLENE/UNSATURATED CARBOXYLIC ACID COPOLYMER, AND SAID COPOLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2017-01-05 US disclosed
EP-3101040-A1 METHOD FOR PRODUCING ETHYLENE/UNSATURATED CARBOXYLIC ACID COPOLYMER, AND SAID COPOLYMER Japan Polyethylene Corporation (JP) 2016-12-07 EP disclosed
CN-105940016-A Method for producing ethylene/unsaturated carboxylic acid copolymer, and said copolymer 日本聚乙烯株式会社 2016-09-14 CN disclosed
US-20160237184-A1 IMINE COMPOUND, NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2016-08-18 US disclosed
EP-3050892-A1 IMINE COMPOUND AND NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2016-08-03 EP disclosed
CN-105593235-A Imine compound, novel catalyst for olefin polymerization, and method for producing olefin polymer JAPAN POLYPROPYLENE CORP 2016-05-18 CN disclosed
US-8618319-B2 Metal complex and method for producing α-olefin polymer and method for producing α-olefin/(meth)acrylate copolymer using the same JAPAN POLYPROPYLENE CORPORATION (JP) 2013-12-31 US disclosed
US-20110213110-A1 NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160237184-A1 IMINE COMPOUND, NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER ODC1, MACF1, MOGAT2 KCNH2 3423/4885KCNA3 4447/4885APP 1774/4885
US-20110213110-A1 NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME OPRD1, OSTC, COG7 KCNH2 3623/4885KCNA3 3538/4885APP 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.