SCHEMBL24658347

SCHEMBL24658347

CCN1CC(O)N(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.39
GBA1 P04062 2/20 0.34
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
ADRA2C P18825 1/20 0.32
F2 P00734 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CTRC Q99895 1/20 0.32
GAA P10253 2/20 0.31
TP53 P04637 1/20 0.31
BRD4 O60885 1/20 0.31
MAPK1 P28482 1/20 0.30
ABL1 P00519 1/20 0.30
RIN1 Q13671 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18746200 0.75
SCHEMBL1020591 0.73
SCHEMBL22728675 0.67 RIPK1 (0.45) P2RX7KMT2ABRD4
SCHEMBL7973427 0.67
SCHEMBL7246666 0.67 ALOX5 (0.35) P2RX7L3MBTL1F2ELANECTSG
SCHEMBL15086890 0.67 MAPT (0.40) P2RX7KMT2AADRA2CMAPK1
SCHEMBL19866225 0.67
SCHEMBL22795975 0.64 GAA (0.34) L3MBTL1F2ELANECTSGCTRC
SCHEMBL4032366 0.64 TP53 (0.33) L3MBTL1F2ELANECTSGCTRC
SCHEMBL1830394 0.64 L3MBTL1 (0.38) L3MBTL1F2ELANECTSGCTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022189856-A9 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2022-10-13 WO disclosed