Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058148 | 0.87 | HCAR3 (0.54) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL24660362 | 0.86 | MAPK1 (0.49) | NNMTGAAPOLBMEN1NPC1 | |
| SCHEMBL5734042 | 0.86 | NNMT (0.58) | NNMTEPHX2SMN1; SMN2 | |
| SCHEMBL31165993 | 0.83 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL7908261 | 0.83 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL14479082 | 0.83 | GAA (0.41) | NNMTGAAPOLBMEN1NPC1 | |
| SCHEMBL25752898 | 0.81 | RAB9A (0.50) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL15758463 | 0.80 | RAB9A (0.46) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL25205986 | 0.80 | GRM5 (0.53) | POLBMEN1KMT2A | |
| SCHEMBL8124860 | 0.80 | GAA (0.39) | GAAPOLBMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178592-A1 | SOLID PHASE SYNTHESIS OF GLUTAMATE-UREA-LYSINE DERIVED (GUL DERIVED) PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) TARGETING CONJUGATES AND THEIR USE AS PRECURSORS FOR THERAPEUTIC AND / OR DIAGNOSTIC AGENTS | Telix International Pty Ltd (AU) | 2022-09-01 | — | — | WO | disclosed |