Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31165993 | 1.00 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL56219 | 0.85 | PTGS1 (0.50) | RAB9APTGS1MAPKAPK2HDAC1GSK3B | |
| SCHEMBL25752898 | 0.84 | RAB9A (0.50) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL24660418 | 0.83 | NNMT (0.55) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL15758463 | 0.82 | RAB9A (0.46) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL27938545 | 0.82 | GAA (0.45) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL2058148 | 0.81 | HCAR3 (0.54) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL24660362 | 0.80 | MAPK1 (0.49) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL15600409 | 0.80 | GAA (0.70) | GAAPOLBMEN1NPC1RAB9A | |
| SCHEMBL27838436 | 0.80 | GAA (0.46) | GAAPOLBMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437062-B | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114437062-A | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-102227218-B | Tnik inhibitor and use thereof | CARNA BIOSCIENCES INC | 2014-04-02 | — | — | CN | disclosed |
| CN-103153063-A | Quinoline derivatives and MELK inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2013-06-12 | — | — | CN | disclosed |
| CN-102227218-A | Tnik inhibitor and use thereof | TESSHI YAMADA | 2011-10-26 | — | — | CN | disclosed |
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | disclosed |
| EP-0667859-B1 | MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES | ANORMED INC (CA) | 2000-08-23 | — | — | EP | disclosed |
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5679778-A | FOR FORMING CONJUGATES WITH MACROMOLECULES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5420285-A | Imaging for medicine | JOHNSON MATTHEY, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| WO-1994010149-A1 | MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1994-05-11 | — | — | WO | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |