Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126145 | 0.84 | RAB9A (0.62) | RAB9AMAPTGAAPOLBNPC1 | |
| SCHEMBL31165993 | 0.84 | GAA (0.45) | RAB9AGAAPOLBNPC1MEN1 | |
| SCHEMBL15758463 | 0.84 | RAB9A (0.46) | RAB9AMAPTGAAPOLBNPC1 | |
| SCHEMBL7908261 | 0.84 | GAA (0.45) | RAB9AGAAPOLBNPC1MEN1 | |
| SCHEMBL2058148 | 0.82 | HCAR3 (0.54) | RAB9AGAAPOLBNPC1MEN1 | |
| SCHEMBL24660362 | 0.81 | MAPK1 (0.49) | RAB9AGAAPOLBNPC1MEN1 | |
| SCHEMBL27838436 | 0.81 | GAA (0.46) | RAB9AGAAPOLBNPC1MEN1 | |
| SCHEMBL24660418 | 0.81 | NNMT (0.55) | RAB9AGAAPOLBNPC1MEN1 | |
| SCHEMBL15600409 | 0.81 | GAA (0.70) | RAB9AMAPTGAAPOLBNPC1 | |
| SCHEMBL27938545 | 0.80 | GAA (0.45) | RAB9AGAAPOLBNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192647-A1 | COMPOUNDS FOR INHIBITION OF FIBROBLAST ACTIVATION PROTEIN | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192647-A1 | COMPOUNDS FOR INHIBITION OF FIBROBLAST ACTIVATION PROTEIN | FAP, FIBP, APC | RAB9A 1243/4885MAPT 4726/4885GAA 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.