SCHEMBL2466292

SCHEMBL2466292

CCCCCCCOc1ccc(C(=O)O)cc1C(F)(F)F

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.70
THRB P10828 2/20 0.70
PLA2G2D Q9UNK4 1/20 0.65
ALDH1A1 P00352 1/20 0.60
HPGD P15428 1/20 0.60
PTPN11 Q06124 2/20 0.59
S1PR1 P21453 3/20 0.58
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
PLA2G4B P0C869 1/20 0.55
PLA2G2A P14555 1/20 0.52
RARB P10826 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1171751 1.00 THRA (0.70) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL4785017 0.99 THRA (0.68) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL27669784 0.96 THRA (0.65) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL3171378 0.92 THRA (0.61) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL2593666 0.92 THRA (0.59) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL2957056 0.90 THRA (0.69) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL27754609 0.89 THRA (0.74) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL25789823 0.89 PLA2G2D (0.65) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL9307228 0.87 THRA (0.70) THRATHRBPLA2G2DALDH1A1HPGD
SCHEMBL9307582 0.87 THRA (0.70) THRATHRBPLA2G2DALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3819285-B1 4-ALKOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL PRODUCTION METHOD MITSUBISHI TANABE PHARMA CORP (JP) 2022-06-08 EP disclosed
EP-3819285-A1 4-ALKOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL PRODUCTION METHOD Mitsubishi Tanabe Pharma Corporation (JP) 2021-05-12 EP disclosed
EP-3492448-B1 4-ALKOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL PRODUCTION METHOD MITSUBISHI TANABE PHARMA CORP (JP) 2021-03-03 EP disclosed
US-10752575-B2 4-alkoxy-3-(trifluoromethyl)benzyl alcohol production method MITSUBISHI TANABE PHARMA CORPORATION (JP) 2020-08-25 US disclosed
EP-3492448-A1 4-ALKOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL PRODUCTION METHOD Mitsubishi Tanabe Pharma Corporation (JP) 2019-06-05 EP disclosed
US-20190161432-A1 4-ALKOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL PRODUCTION METHOD MITSUBISHI TANABE PHARMA CORPORATION (JP) 2019-05-30 US disclosed
US-20140296183-A1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES MITSUBISHI TANABE PHARMA CORP (JP) 2014-10-02 US disclosed
US-20140296183-A1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES MITSUBISHI TANABE PHARMA CORP (JP) 2014-10-02 US disclosed
US-20140296183-A1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES MITSUBISHI TANABE PHARMA CORP (JP) 2014-10-02 US disclosed
US-8809304-B2 Amine compound and use thereof for medical purposes MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-08-19 US disclosed
US-8809304-B2 Amine compound and use thereof for medical purposes MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-08-19 US disclosed
US-8809304-B2 Amine compound and use thereof for medical purposes MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-08-19 US disclosed
EP-1961734-B1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES MITSUBISHI TANABE PHARMA CORP (JP) 2011-09-14 EP disclosed
EP-1961734-B1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES MITSUBISHI TANABE PHARMA CORP (JP) 2011-09-14 EP disclosed
US-20090137530-A1 Amine Compound and Use Thereof for Medical Purposes MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-05-28 US disclosed
US-20090137530-A1 Amine Compound and Use Thereof for Medical Purposes MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-05-28 US disclosed
US-20090137530-A1 Amine Compound and Use Thereof for Medical Purposes MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-05-28 US disclosed
EP-1961734-A1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES Mitsubishi Tanabe Pharma Corporation (JP) 2008-08-27 EP disclosed
EP-1961734-A1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES Mitsubishi Tanabe Pharma Corporation (JP) 2008-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137530-A1 Amine Compound and Use Thereof for Medical Purposes HRH3, HRH2, HRH4 THRA 705/4885THRB 536/4885PLA2G2D 3558/4885
US-20190161432-A1 4-ALKOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL PRODUCTION METHOD ADH1C, ADH5, ADH1A THRA 2107/4885THRB 1031/4885PLA2G2D 3877/4885
US-10752575-B2 4-alkoxy-3-(trifluoromethyl)benzyl alcohol production method ADH1C, ADH5, ADH1A THRA 2107/4885THRB 1031/4885PLA2G2D 3877/4885
US-20140296183-A1 AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES HRH3, HRH2, HRH4 THRA 705/4885THRB 536/4885PLA2G2D 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.