Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | IL36G | Q9NZH8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470067 | 0.91 | ALPL (0.40) | KMOKDM4ELMNATP53MAPT | |
| SCHEMBL2463132 | 0.90 | ABL1 (0.42) | KMOTP53MAPT | |
| SCHEMBL2465141 | 0.88 | KMO (0.48) | KMOKDM4EMAPT | |
| SCHEMBL2466248 | 0.87 | MAPT (0.44) | KDM4ELMNATP53MAPT | |
| SCHEMBL2464675 | 0.86 | KMO (0.34) | KMOKDM4EMAPTIL36G | |
| SCHEMBL2469327 | 0.85 | KMO (0.47) | KMO | |
| SCHEMBL2468817 | 0.85 | DHODH (0.45) | KMOLMNAMAPT | |
| SCHEMBL2466313 | 0.84 | MAPT (0.43) | KMOKDM4ELMNAMAPT | |
| SCHEMBL2468160 | 0.84 | CTRC (0.46) | KMOKDM4ETP53MAPT | |
| SCHEMBL2470000 | 0.83 | ACHE (0.45) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |