SCHEMBL246677

SCHEMBL246677

CC(=COCOCC(C)C)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1897488 1.00 TSHR (0.32) TSHR
SCHEMBL1900609 0.85 TSHR (0.36) TSHR
SCHEMBL569637 0.85 TSHR (0.36) TSHR
SCHEMBL28479819 0.77 TSHR (0.32) TSHR
SCHEMBL4038150 0.74 TSHR (0.34) TSHR
SCHEMBL7595709 0.74 TSHR (0.34) TSHR
SCHEMBL8676453 0.74 ALDH1A1 (0.38) TSHR
SCHEMBL248080 0.73 TSHR (0.33) TSHR
SCHEMBL5072346 0.70
SCHEMBL10500586 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3449904-B1 EMULSIFIED COSMETIC SHINETSU CHEMICAL CO (JP) 2024-06-19 EP claimed
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER OREAL (FR) 2025-12-18 US disclosed
WO-2025132142-A1 INVERT EMULSION COMPRISING PULLULAN, AN APOLAR HYDROCARBON-BASED OIL, A SILICONE FILM-FORMING POLYMER AND A DYESTUFF, AND MAKEUP PROCESS L'OREAL (FR) 2025-06-26 WO disclosed
WO-2025082655-A1 LOW WATER CONTENT W/O EMULSION COMPRISING A HYDROPHOBIC FILM-FORMING POLYMER, A LINEAR SILICONE POLYOL, HYALURONIC ACID, A VITAMIN B3 AND A XANTHINE BASE L'OREAL (FR) 2025-04-24 WO disclosed
WO-2025061338-A1 SOLID COMPOSITION IN POWDER FORM COMPRISING A FILM-FORMING POLYMER IN THE SOLID STATE L'OREAL (FR) 2025-03-27 WO disclosed
WO-2025061352-A1 PROCESS FOR PREPARING A COSMETIC COMPOSITION COMPRISING A PULVERULENT PHASE AND A FILM-FORMING POLYMER SOLUBILIZED IN A VOLATILE SOLVENT; AND PIGMENT FORMULATION. L'OREAL (FR) 2025-03-27 WO disclosed
US-20250099363-A1 COSMETIC WATER-IN-OIL EMULSION COMPRISING A SPECIFIC WATER-SOLUBLE UV SCREENING AGENT, A BASE, A VOLATILE OIL, A HYDROPHOBIC FILM-FORMING POLYMER, A POLYOXYALKYLENATED LINEAR POLYDIMETHYLMETHYLSILOXANE AND A VITAMIN B3 L'OREAL (FR) 2025-03-27 US disclosed
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER L'OREAL (FR) 2025-02-06 US disclosed
US-12186417-B2 Skin perfecting cosmetic compositions and methods of use L'OREAL (FR) 2025-01-07 US disclosed
US-20240374486-A1 COSMETIC MAKE-UP COMPOSITION L V M H RECHERCHE (FR) 2024-11-14 US disclosed
US-20020120039-A1 Vinyl copolymer emulsion DOW TORAY CO., LTD. (JP) 2002-08-29 US disclosed
US-6291021-B1 MATERIAL COMPRISING PENDANT CARBOSILOXANE-DENDRIMER FUNCTIONAL VINYL-TYPE POLYMER COMPRISING CARBOSILOXANE DENDRIMER GROUP AND ACRYLIC RESIN WHICH DOES NOT CONTAIN PENDANT CARBOSILOXANE DENDRIMER STRUCTURE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2001-09-18 US disclosed
US-6280748-B1 TREATING SKIN OR HAIR BY APPLYING TO SKIN OR HAIR COSMETIC PRODUCT COMPRISING SOLUTION OR DISPERSION OF POLYMER IN LIQUID SELECTED FROM SILICONE OILS, ORGANIC OILS, ALCOHOLS AND WATER, POLYMER HAVING CARBOSILOXANE DENDRIMER IN ITS SIDE CHAIN DOW CORNING TORAY SILICONE, LTD. (JP) 2001-08-28 US disclosed
US-6238745-B1 APPLYING CARBOSILOXANE POLYMER DOW CORNING TORAY SILICONE CO. LTD. (JP) 2001-05-29 US disclosed
EP-1095953-A2 Silicone-grafted vinyl copolymer emulsion composition Dow Corning Toray Silicone Company, Ltd. (JP) 2001-05-02 EP disclosed
EP-1013702-A2 Gas-permeable film Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1013736-A2 Water repellent for treating solids Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 EP disclosed
EP-1006165-A2 Coating material Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-07 EP disclosed
EP-0963751-A2 Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material Dow Corning Toray Silicone Company, Ltd. (JP) 1999-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12186417-B2 Skin perfecting cosmetic compositions and methods of use CUTA, DSG1, SMURF1 TSHR 1097/4885
US-20240374486-A1 COSMETIC MAKE-UP COMPOSITION KRT18, DEGS1, CUTA TSHR 4062/4885
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER H1-0, PARN, FASN TSHR 1030/4885
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER CCNO, CUTA, SQLE TSHR 3701/4885
US-20250099363-A1 COSMETIC WATER-IN-OIL EMULSION COMPRISING A SPECIFIC WATER-SOLUBLE UV SCREENING AGENT, A BASE, A VOLATILE OIL, A HYDROPHOBIC FILM-FORMING POLYMER, A POLYOXYALKYLENATED LINEAR POLYDIMETHYLMETHYLSILOXANE AND A VITAMIN B3 KRT18, RARB, RXRB TSHR 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.