SCHEMBL248080

SCHEMBL248080

CC(C)COCOC=CC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MAP3K7 O43318 2/20 0.33
TAB1 Q15750 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2832059 0.84 TSHR (0.38) TSHRMAP3K7TAB1ALDH1A1MAPT
SCHEMBL18294835 0.73 MAP3K7 (0.38) TSHRMAP3K7TAB1ALDH1A1MAPT
SCHEMBL8649318 0.73 MAP3K7 (0.38) TSHRMAP3K7TAB1ALDH1A1MAPT
SCHEMBL1897488 0.73 TSHR (0.32) TSHR
SCHEMBL246677 0.73 TSHR (0.32) TSHR
SCHEMBL181556 0.70 TSHR (0.33) TSHRMAP3K7TAB1ALDH1A1MAPT
SCHEMBL10583087 0.70
Urea SCHEMBL8376677 0.70 TSHR (0.41) TSHRALDH1A1MAPT
SCHEMBL693825 0.69
SCHEMBL3387617 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER OREAL (FR) 2025-12-18 US disclosed
US-12220479-B2 Suncare formulation ROHM AND HAAS COMPANY (US) 2025-02-11 US disclosed
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER L'OREAL (FR) 2025-02-06 US disclosed
US-12151015-B2 Color cosmetic formulation DOW GLOBAL TECHNOLOGIES LLC (US) 2024-11-26 US disclosed
EP-4452193-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER L'OREAL (FR) 2024-10-30 EP disclosed
US-12128125-B2 Polymer blend DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-29 US disclosed
EP-4263712-B1 METHOD OF PREPARING FILM AND COMPOSITION THEREFOR DOW SILICONES CORP (US) 2024-10-09 EP disclosed
CN-118382418-A Cosmetic composition comprising polyhydroxyalkanoate copolymer with (unsaturated) hydrocarbon-based chain and silicone polymer 欧莱雅 2024-07-23 CN disclosed
EP-3435962-B1 DEVICE FOR APPLYING A COMPOSITION IN THE FORM OF AN EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS OREAL (FR) 2024-05-22 EP disclosed
CN-113164793-B Polymer blends for personal care formulations 陶氏环球技术有限责任公司 2024-05-17 CN disclosed
WO-2006011676-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO., LTD. (JP) 2006-02-02 WO disclosed
US-20050008597-A1 Cosmetic raw material cosmetic product and method for manufacturing a cosmetic product DOW TORAY CO., LTD. (JP) 2005-01-13 US disclosed
WO-2004076560-A1 THERMOPLASTIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2004-09-10 WO disclosed
WO-2004076547-A1 INORGANIC-POWDER TREATMENT AGENT, INORGANIC POWDER TREATED WITH THE SAME, AND THERMOPLASTIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-09-10 WO disclosed
EP-1448154-A2 COSMETIC RAW MATERIAL, COSMETIC PRODUCT, AND METHOD FOR MANUFACTURING A COSMETIC PRODUCT Dow Corning Toray Silicone Company, Ltd. (JP) 2004-08-25 EP disclosed
US-6602949-B2 Copolymer of a vinyl monomer, a branched organosilicon compound having an ethenically unsaturated group, and a radically polymerizable surfactant; water repellent coatings with printability, storage stability DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-08-05 US disclosed
WO-2003045337-A2 COSMETIC RAW MATERIAL, COSMETIC PRODUCT, AND METHOD FOR MANUFACTURING A COSMETIC PRODUCT DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-06-05 WO disclosed
US-6534590-B1 Vinyl monomer, carbosiloxane dendrimer, surfactant, and free radical initiator; waterproof coatings; storage stability DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-03-18 US disclosed
US-20020120039-A1 Vinyl copolymer emulsion DOW TORAY CO., LTD. (JP) 2002-08-29 US disclosed
EP-1095953-A2 Silicone-grafted vinyl copolymer emulsion composition Dow Corning Toray Silicone Company, Ltd. (JP) 2001-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12128125-B2 Polymer blend MMAB, MMS19, C9 TSHR 2929/4885MAP3K7 3355/4885TAB1 3027/4885
US-12151015-B2 Color cosmetic formulation FDFT1, CAD, SCD5 TSHR 2892/4885MAP3K7 2823/4885TAB1 3955/4885
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER H1-0, PARN, FASN TSHR 1030/4885MAP3K7 3928/4885TAB1 3977/4885
US-12220479-B2 Suncare formulation MMS19, TLR7, CD40LG TSHR 3879/4885MAP3K7 2923/4885TAB1 3075/4885
US-20050008597-A1 Cosmetic raw material cosmetic product and method for manufacturing a cosmetic product CUTA, CD40LG, FSCN1 TSHR 1890/4885MAP3K7 3146/4885TAB1 3618/4885
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER CCNO, CUTA, SQLE TSHR 3701/4885MAP3K7 3974/4885TAB1 4604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.