Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670563 | 0.78 | KDM4E (0.37) | GBA1 | |
| SCHEMBL19986855 | 0.75 | — | — | |
| SCHEMBL24744819 | 0.73 | KDM4E (0.33) | — | |
| SCHEMBL16939210 | 0.72 | — | — | |
| SCHEMBL11013490 | 0.72 | ALDH1A1 (0.36) | GLB1GBA1S1PR1S1PR3S1PR5 | |
| SCHEMBL25922429 | 0.72 | DRD2 (0.30) | — | |
| SCHEMBL18801000 | 0.72 | LMNA (0.44) | GBA1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL20921365 | 0.69 | S1PR1 (0.47) | GLB1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL18800954 | 0.69 | LMNA (0.41) | GBA1S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL16508917 | 0.69 | NOS3 (0.40) | GLB1GBA1S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679235-A | Azetidine derivatives and their use as prostaglandin E2 antagonists | PFIZER LTD | 2010-03-24 | — | — | CN | disclosed |