Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.39 |
| ▸ | CDK9 | P50750 | 5/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669433 | 0.86 | CCNT1 (0.36) | CCNT1CDK9BRPF1HTR2CHTR6 | |
| SCHEMBL24670925 | 0.81 | CCNT1 (0.41) | CCNT1CDK9BRPF1HTR6PRMT5 | |
| SCHEMBL24670266 | 0.80 | CCNT1 (0.52) | CCNT1CDK9BRPF1HTR6PRMT5 | |
| SCHEMBL29803229 | 0.78 | BRPF1 (0.48) | CCNT1CDK9BRPF1QDPR | |
| SCHEMBL24670321 | 0.76 | QDPR (0.47) | CCNT1CDK9HTR2CHTR6QDPR | |
| SCHEMBL24671346 | 0.74 | PDE3B (0.45) | CCNT1CDK9BRPF1HTR2C | |
| SCHEMBL29803534 | 0.71 | BRPF1 (0.44) | CCNT1CDK9BRPF1HTR2CQDPR | |
| SCHEMBL24091437 | 0.70 | TSHR (0.55) | QDPR | |
| SCHEMBL22924537 | 0.69 | CES2 (0.53) | KCNA3 | |
| SCHEMBL24670907 | 0.69 | CCNT1 (0.38) | CCNT1CDK9HTR2CHTR6QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |