Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443496 | 0.88 | ALOX5 (0.49) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL11239686 | 0.86 | ALDH1A1 (0.85) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Chavicol SCHEMBL4444837 | 0.84 | ALDH1A1 (0.41) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL28883151 | 0.82 | ALDH1A1 (0.93) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL788240 | 0.82 | ALDH1A1 (1.00) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL20361 | 0.82 | ALDH1A1 (1.00) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL29364978 | 0.82 | ALDH1A1 (1.00) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL29126189 | 0.82 | ALDH1A1 (1.00) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL27521002 | 0.80 | TRPM8 (0.90) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 | |
| Eugenol SCHEMBL662388 | 0.80 | TRPM8 (0.90) | TRPM8ALDH1A1ALOX5CYP3A4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530606-B1 | SILOXANE BISCHLOROFORMATES | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-12-08 | — | — | EP | claimed |
| CN-101258158-A | Siloxane bischloroformates | GEN ELECTRIC (US) | 2008-09-03 | — | — | CN | claimed |
| EP-1937693-A1 | SILOXANE BISCHLOROFORMATES | General Electric Company (US) | 2008-07-02 | — | — | EP | claimed |
| CN-1324071-C | Siloxane bischloroformates | GEN ELECTRIC (US) | 2007-07-04 | — | — | CN | claimed |
| US-20070093629-A1 | Siloxane bishchloroformates | GENERAL ELECTRIC COMPANY (US) | 2007-04-26 | — | — | US | claimed |
| WO-2007037888-A1 | SILOXANE BISCHLOROFORMATES | GENERAL ELECTRIC COMPANY (US) | 2007-04-05 | — | — | WO | claimed |
| CN-1688634-A | Siloxane bischloroformates | GEN ELECTRIC (US) | 2005-10-26 | — | — | CN | claimed |
| EP-1530606-A1 | SILOXANE BISCHLOROFORMATES | GENERAL ELECTRIC COMPANY (US) | 2005-05-18 | — | — | EP | claimed |
| US-6780956-B2 | FOR CONTROLLING PHYSICAL PROPERTIES OF POLYCARBONATESILOXANE COPOLYMERS; FOR PRODUCTION OF OPTICAL DISKS | GENERAL ELECTRIC COMPANY | 2004-08-24 | — | — | US | claimed |
| US-20040133024-A1 | Siloxane bischloroformates | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2004-07-08 | — | — | US | claimed |
| US-6723864-B2 | CONTINUOUS PROCESS BY PHOSGENATING SILOXANE BISPHENOLS IN A FLOW REACTOR USING A SUBSTANTIAL EXCESS OF PHOSGENE AND SODIUM HYDROXIDE | GENERAL ELECTRIC COMPANY | 2004-04-20 | — | — | US | claimed |
| WO-2004016675-A1 | SILOXANE BISCHLOROFORMATES | GENERAL ELECTRIC COMPANY (US) | 2004-02-26 | — | — | WO | claimed |
| US-20040039218-A1 | A continuous process by phosgenating siloxane bisphenols in a flow reactor using a substantial excess of phosgene and sodium hydroxide to achieve high yields and very pure product; intermediates for polycarbonatesiloxanes | GENERAL ELECTRIC COMPANY | 2004-02-26 | — | — | US | claimed |
| US-20030065122-A1 | Method of making silicone copolycarbonates having random and blocky substructures | GENERAL ELECTRIC COMPANY | 2003-04-03 | — | — | US | claimed |
| US-6492481-B1 | THE SILICONE COPOLYCARBONATES CONTAIN RESIDUES OF SILICONE CONTAINING AND NONSILICONE CONTAINING BISPHENOLS AND HAVE PROPERTIES PARTICULARLY SUITED FOR USE IN HIGH DENSITY OPTICAL DATA STORAGE MEDIA. THE PROPERTIES OF SUBSTANTIALLY SINGLE | GENERAL ELECTRIC COMPANY | 2002-12-10 | — | — | US | claimed |
| EP-1235872-A1 | SUBSTANTIALLY SINGLE PHASE SILICONE COPOLYCARBONATES, METHODS, AND OPTICAL ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2002-09-04 | — | — | EP | claimed |
| WO-2002004545-A1 | SUBSTANTIALLY SINGLE PHASE SILICONE COPOLYCARBONATES, METHODS, AND OPTICAL ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2002-01-17 | — | — | WO | claimed |
| EP-1963399-B1 | POLYCYCLIC DIHYDROXY COMPOUNDS AND METHODS FOR PREPARATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-07-27 | — | — | EP | disclosed |
| EP-1235872-A1 | SUBSTANTIALLY SINGLE PHASE SILICONE COPOLYCARBONATES, METHODS, AND OPTICAL ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2002004545-A1 | SUBSTANTIALLY SINGLE PHASE SILICONE COPOLYCARBONATES, METHODS, AND OPTICAL ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133024-A1 | Siloxane bischloroformates | PSMA2, PSMA3, PSMA4 | TRPM8 3424/4885ALDH1A1 3970/4885ALOX5 2032/4885 |
| US-20040039218-A1 | A continuous process by phosgenating siloxane bisphenols in a flow reactor using a substantial excess of phosgene and sodium hydroxide to achieve high yields and very pure product; intermediates for polycarbonatesiloxanes | PSPH, PAH, SEM1 | TRPM8 3280/4885ALDH1A1 4036/4885ALOX5 1919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.