Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 15/20 | 0.50 |
| ▸ | CDK9 | P50750 | 15/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803778 | 1.00 | CCNT1 (0.50) | CCNT1CDK9BRPF1KCNQ3KCNQ2 | |
| SCHEMBL24671483 | 0.87 | JAK1 (0.42) | CCNT1CDK9 | |
| SCHEMBL29803524 | 0.84 | CCNT1 (0.49) | CCNT1CDK9BRPF1KCNQ3KCNQ2 | |
| SCHEMBL29803336 | 0.83 | CCNT1 (0.48) | CCNT1CDK9BRPF1NPC1RAB9A | |
| SCHEMBL29803411 | 0.83 | CCNT1 (0.49) | CCNT1CDK9KCNQ3KCNQ2MAOB | |
| SCHEMBL29803282 | 0.83 | CCNT1 (0.49) | CCNT1CDK9KCNQ3KCNQ2NPC1 | |
| SCHEMBL24670849 | 0.82 | BRPF1 (0.49) | CCNT1CDK9BRPF1NPC1CYP1A2 | |
| SCHEMBL29803697 | 0.82 | BRPF1 (0.49) | CCNT1CDK9BRPF1NPC1CYP1A2 | |
| SCHEMBL24670221 | 0.81 | QDPR (0.51) | CCNT1CDK9BRPF1NPC1CYP1A2 | |
| SCHEMBL29803895 | 0.81 | QDPR (0.51) | CCNT1CDK9BRPF1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |