Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 9/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669665 | 0.86 | NAMPT (0.48) | ABCB1NPC1RAB9AMITFTP53 | |
| SCHEMBL24670310 | 0.80 | PDE4B (0.43) | ABCB1NPC1RAB9AMITFTP53 | |
| SCHEMBL29803430 | 0.79 | NAMPT (0.44) | ABCB1NPC1RAB9AMITFTP53 | |
| SCHEMBL24671576 | 0.79 | NAMPT (0.44) | ABCB1NPC1RAB9AMITFTP53 | |
| SCHEMBL24670528 | 0.79 | NAMPT (0.46) | NPC1RAB9ANAMPT | |
| SCHEMBL29802891 | 0.78 | APOBEC3A (0.49) | RAB9AQDPRNAMPTKDM4EKMT2A | |
| SCHEMBL29803621 | 0.77 | QDPR (0.54) | ABCB1NPC1RAB9AMITFTP53 | |
| SCHEMBL24671431 | 0.76 | NAMPT (0.48) | NAMPT | |
| SCHEMBL24670801 | 0.75 | TMPRSS2 (0.45) | QDPRNAMPTKDM4EKMT2A | |
| SCHEMBL24671261 | 0.74 | QDPR (0.43) | ABCB1NPC1RAB9AQDPRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |