Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673250 | 0.92 | SIGMAR1 (0.56) | APOBEC3ARECQLAPOBEC3GKDM4EMEN1 | |
| SCHEMBL24672258 | 0.88 | KDM4E (0.51) | APOBEC3ARECQLAPOBEC3GKDM4EMEN1 | |
| SCHEMBL24673327 | 0.81 | POLB (0.53) | KDM4EMEN1KMT2AATMALDH1A1 | |
| SCHEMBL24672849 | 0.79 | LMNA (0.47) | KDM4ESIGMAR1LMNAGAA | |
| SCHEMBL24673197 | 0.78 | KDM4E (0.45) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL24672858 | 0.77 | HDAC4 (0.46) | APOBEC3ARECQLAPOBEC3GMEN1KMT2A | |
| SCHEMBL3312142 | 0.77 | KMT2A (0.69) | APOBEC3ARECQLAPOBEC3GKDM4EMEN1 | |
| SCHEMBL4473753 | 0.76 | KDM4E (0.59) | KDM4EMEN1KMT2ASIGMAR1ATM | |
| SCHEMBL24673200 | 0.76 | PKM (0.43) | APOBEC3ARECQLAPOBEC3GKDM4EMEN1 | |
| SCHEMBL24673196 | 0.76 | HDAC1 (0.47) | APOBEC3ARECQLAPOBEC3GKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204065-A1 | IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |