Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673250 | 0.85 | SIGMAR1 (0.56) | POLBALDH1A1LMNAATMMEN1 | |
| SCHEMBL24673197 | 0.82 | KDM4E (0.45) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24672858 | 0.82 | HDAC4 (0.46) | ALDH1A1LMNAATMMEN1KMT2A | |
| SCHEMBL24673260 | 0.81 | APOBEC3A (0.51) | POLBALDH1A1LMNAATMMEN1 | |
| SCHEMBL24673209 | 0.81 | PGK1 (0.41) | ALDH1A1LMNAATMMEN1KMT2A | |
| SCHEMBL24672258 | 0.80 | KDM4E (0.51) | POLBALDH1A1LMNAATMMEN1 | |
| SCHEMBL24672262 | 0.79 | POLB (0.38) | POLBLMNAKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24673200 | 0.78 | PKM (0.43) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24673196 | 0.78 | HDAC1 (0.47) | ALDH1A1LMNAATMMEN1KMT2A | |
| SCHEMBL7989530 | 0.77 | LMNA (0.83) | POLBALDH1A1LMNAATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204065-A1 | IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |