SCHEMBL24673250

SCHEMBL24673250

OC[C@@H](O)[C@@H](CO)N1CCN(Cc2ccccc2)CCN([C@H](CO)[C@H](O)CO)CC1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.56
KDM4E B2RXH2 2/20 0.53
ATM Q13315 1/20 0.52
APOBEC3A P31941 1/20 0.51
RECQL P46063 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 2/20 0.49
GAA P10253 1/20 0.49
MC4R P32245 1/20 0.49
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
DRD4 P21917 1/20 0.47
POLB P06746 1/20 0.47
IGF1R P08069 1/20 0.47
PHGDH O43175 1/20 0.46
MGLL Q99685 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673260 0.92 APOBEC3A (0.51) SIGMAR1KDM4EATMAPOBEC3ARECQL
SCHEMBL24672258 0.91 KDM4E (0.51) SIGMAR1KDM4EATMAPOBEC3ARECQL
SCHEMBL24672849 0.86 LMNA (0.47) SIGMAR1KDM4ELMNAGAAIGF1R
SCHEMBL24673197 0.85 KDM4E (0.45) KDM4EMEN1KMT2AALDH1A1POLB
SCHEMBL24673327 0.85 POLB (0.53) KDM4EATMMEN1KMT2ALMNA
SCHEMBL24672858 0.84 HDAC4 (0.46) ATMAPOBEC3ARECQLAPOBEC3GMEN1
SCHEMBL24672676 0.81 MPO (0.63) KDM4EATMMEN1KMT2ALMNA
SCHEMBL24672677 0.81 MPO (0.63) KDM4EATMMEN1KMT2ALMNA
SCHEMBL24673209 0.80 PGK1 (0.41) KDM4EATMAPOBEC3ARECQLAPOBEC3G
SCHEMBL3319719 0.80 SIGMAR1 (0.64) SIGMAR1KDM4EATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed