Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695939 | 0.85 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL2816305 | 0.84 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL6676173 | 0.84 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL7721059 | 0.84 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| Hydrochloric Acid SCHEMBL8053510 | 0.83 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL9293364 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| Hydrochloric Acid SCHEMBL6678335 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL7378770 | 0.83 | CA1 (0.58) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL11622577 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1CA1CA2 | |
| SCHEMBL7416290 | 0.83 | CA1 (0.55) | ALDH1A1L3MBTL1MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | IL1B, IL1A, CASP1 | ALDH1A1 226/4885L3MBTL1 4200/4885MAPK1 580/4885 |
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, BRCA1 | ALDH1A1 2600/4885L3MBTL1 1084/4885MAPK1 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.