Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673965 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HTT | |
| SCHEMBL24673556 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HTT | |
| SCHEMBL24673966 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HTT | |
| SCHEMBL22797551 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL22797550 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL22797486 | 0.73 | ALDH1A1 (0.32) | ALDH1A1CYP3A4 | |
| SCHEMBL22797482 | 0.73 | ALDH1A1 (0.32) | ALDH1A1CYP3A4 | |
| SCHEMBL24673034 | 0.73 | OPRM1 (0.32) | — | |
| SCHEMBL18379865 | 0.71 | SMYD2 (0.35) | ALDH1A1CYP3A4HTTSMN1; SMN2GLB1 | |
| SCHEMBL10321660 | 0.70 | ALDH1A1 (0.31) | ALDH1A1CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220275018-A1 | NOVEL SPIROBICYCLIC INTERMEDIATES | JANSSEN PHARMACEUTICA NV (BE) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220275018-A1 | NOVEL SPIROBICYCLIC INTERMEDIATES | NME2, SLC28A1, SLC28A2 | ALDH1A1 248/4885CYP3A4 969/4885HTT 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.