Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673966 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53HTTL3MBTL1 | |
| SCHEMBL24673556 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53HTTL3MBTL1 | |
| SCHEMBL24673828 | 0.80 | ALDH1A1 (0.32) | ALDH1A1HTT | |
| SCHEMBL10321660 | 0.70 | ALDH1A1 (0.31) | ALDH1A1HTT | |
| SCHEMBL12509362 | 0.70 | ALDH1A1 (0.31) | ALDH1A1HTT | |
| SCHEMBL22797482 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL22797486 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL31252043 | 0.69 | HTT (0.40) | ALDH1A1TSHRTP53HTTL3MBTL1 | |
| SCHEMBL24673034 | 0.69 | OPRM1 (0.32) | — | |
| SCHEMBL26455239 | 0.69 | GAA (0.33) | ALDH1A1TSHRMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220275018-A1 | NOVEL SPIROBICYCLIC INTERMEDIATES | JANSSEN PHARMACEUTICA NV (BE) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220275018-A1 | NOVEL SPIROBICYCLIC INTERMEDIATES | NME2, SLC28A1, SLC28A2 | ALDH1A1 248/4885TSHR 3334/4885TP53 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.