SCHEMBL24673931

SCHEMBL24673931

C=C(C)c1ccc(C(=O)c2ccc(C#Cc3ccccc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
VCP P55072 1/20 0.49
GRM5 P41594 2/20 0.46
ELANE P08246 2/20 0.46
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP12 P39900 1/20 0.45
MMP14 P50281 1/20 0.45
MMP15 P51511 1/20 0.45
MMP16 P51512 1/20 0.45
MMP26 Q9NRE1 1/20 0.45
ALDH1A1 P00352 2/20 0.45
FFAR1 O14842 4/20 0.44
SRD5A2 P31213 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
APP P05067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6368721 0.85 VCP (0.66) VCPGRM5MMP2MMP9MMP12
SCHEMBL2678763 0.85 ALDH1A1 (0.64) ELANEALDH1A1SRD5A2L3MBTL1
SCHEMBL1744898 0.85 ALDH1A1 (0.64) VCPGRM5MMP2MMP9MMP12
SCHEMBL16582661 0.81 ALDH1A1 (0.61) VCPELANEALDH1A1FFAR1SRD5A2
SCHEMBL84284 0.81 VCP (0.51) VCPGRM5MMP2MMP9MMP12
SCHEMBL9355735 0.80 ALDH1A1 (0.62) ELANEALDH1A1SRD5A2L3MBTL1
SCHEMBL5072017 0.79 LMNA (0.62) ALDH1A1FFAR1SRD5A2L3MBTL1APP
SCHEMBL400497 0.79 MAPT (0.59) VCPGRM5MMP2MMP9MMP12
SCHEMBL4358220 0.78 SRD5A2 (0.59) ALDH1A1FFAR1SRD5A2L3MBTL1APP
SCHEMBL5744049 0.78 MAPT (0.69) GRM5ALDH1A1FFAR1SRD5A2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230034754-A1 ORGANIC SOLID CRYSTAL - METHOD AND STRUCTURE FACEBOOK TECHNOLOGIES, LLC 2023-02-02 US disclosed
US-20220350065-A1 MULTILAYER ORGANIC SOLID THIN FILMS HAVING A BIAXIAL REFRACTIVE INDEX META PLATFORMS TECHNOLOGIES, LLC 2022-11-03 US disclosed