SCHEMBL24676473

SCHEMBL24676473

CSN1CCC(Nc2cc(-c3sc(CO)nc3C(F)(F)F)c(F)cn2)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 18/20 0.35
CCNT1 O60563 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24676472 0.86 TDO2 (0.42) CCNT1
SCHEMBL24676003 0.85 CDK4 (0.44) RORCCCNT1
SCHEMBL24676697 0.78 RORC (0.37) RORCCCNT1
SCHEMBL24675989 0.78 CDK2 (0.37) CCNT1
SCHEMBL24676470 0.77 CDK2 (0.37) CCNT1
SCHEMBL24675981 0.76 CDK2 (0.43) CCNT1
SCHEMBL24676911 0.76 CDK4 (0.38) CCNT1
SCHEMBL24676701 0.76 GPR119 (0.42) RORCCCNT1
SCHEMBL29754809 0.76 GPR119 (0.42) RORCCCNT1
SCHEMBL24676822 0.76 CDK2 (0.41) RORCCCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed