Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676695 | 0.89 | GPR119 (0.46) | RORCGPR119 | |
| SCHEMBL24676945 | 0.80 | RORC (0.38) | RORCCCNT1GPR119SYK | |
| SCHEMBL24676003 | 0.80 | CDK4 (0.44) | RORCCCNT1 | |
| SCHEMBL24676815 | 0.80 | AAK1 (0.35) | — | |
| SCHEMBL24676473 | 0.78 | RORC (0.35) | RORCCCNT1 | |
| SCHEMBL24676814 | 0.72 | AAK1 (0.39) | — | |
| SCHEMBL24676942 | 0.70 | CDK2 (0.43) | CCNT1SYK | |
| SCHEMBL24676002 | 0.69 | CDK2 (0.49) | CCNT1GPR119DYRK2 | |
| SCHEMBL29754964 | 0.69 | CDK2 (0.49) | CCNT1GPR119DYRK2 | |
| SCHEMBL24676460 | 0.67 | RAB9A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |