Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676815 | 0.91 | AAK1 (0.35) | AAK1HTR2CSLC6A4ABL1 | |
| SCHEMBL24676475 | 0.72 | RAB9A (0.34) | PI4KB | |
| SCHEMBL24676697 | 0.72 | RORC (0.37) | — | |
| SCHEMBL24676695 | 0.71 | GPR119 (0.46) | — | |
| SCHEMBL24676708 | 0.71 | — | — | |
| SCHEMBL24676459 | 0.68 | CDK4 (0.45) | PI4KB | |
| SCHEMBL24676013 | 0.67 | PAX8 (0.33) | AAK1ABL1 | |
| SCHEMBL24676460 | 0.67 | RAB9A (0.31) | — | |
| SCHEMBL24675993 | 0.66 | ALDH1A1 (0.33) | AAK1HTR2C | |
| SCHEMBL12991909 | 0.64 | PIK3CG (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |