Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 13/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076451 | 0.81 | CXCR4 (0.67) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL5990981 | 0.81 | HRH3 (0.59) | HRH3 | |
| SCHEMBL12503437 | 0.81 | LMNA (0.56) | HRH3ADH1BADH1CADH1AADH7 | |
| SCHEMBL24677480 | 0.81 | ADRB1 (0.47) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL1259387 | 0.78 | CXCR4 (0.81) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL5573232 | 0.78 | CXCR4 (0.78) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL1663338 | 0.78 | SIGMAR1 (0.59) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL28629993 | 0.77 | CXCR4 (0.60) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| Bromide SCHEMBL1257550 | 0.77 | CXCR4 (0.78) | CXCR4SIGMAR1MEN1CHRM2CHRM1 | |
| SCHEMBL5987431 | 0.76 | DRD4 (0.64) | ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178030-A1 | TRPM8 AGONISTS AS COOLING AGENTS AND FOR THE TREATMENT OF DISEASE | Concentric Analgesics, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |