Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.47 |
| ▸ | HTR3B | O95264 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24248164 | 0.84 | ADRB1 (0.45) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3305094 | 0.83 | ALDH1A1 (0.53) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL3304463 | 0.82 | L3MBTL1 (0.54) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL23655342 | 0.82 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL1758061 | 0.81 | ADRB1 (0.55) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24677400 | 0.81 | CXCR4 (0.56) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL23655331 | 0.81 | MAPT (0.53) | ADRB1ADH1BADH1CADH1AADH7 | |
| SCHEMBL23655787 | 0.81 | L3MBTL1 (0.53) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23655583 | 0.81 | ADH1B (0.46) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL23655531 | 0.78 | SMN1; SMN2 (0.49) | ADH1BADH1CADH1AADH7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178030-A1 | TRPM8 AGONISTS AS COOLING AGENTS AND FOR THE TREATMENT OF DISEASE | Concentric Analgesics, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |