Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304463 | 0.82 | L3MBTL1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL12503437 | 0.81 | LMNA (0.56) | HRH3ALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL14368312 | 0.81 | HRH3 (0.59) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24677400 | 0.81 | CXCR4 (0.56) | HRH3 | |
| SCHEMBL15467001 | 0.80 | HRH3 (0.87) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14058774 | 0.80 | HRH3 (0.67) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5987431 | 0.79 | DRD4 (0.64) | ALDH1A1HTTKDM4E | |
| SCHEMBL6321373 | 0.78 | HRH3 (0.56) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14313879 | 0.78 | NCF1 (0.71) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL207661 | 0.78 | HRH3 (0.65) | HRH3HIF1AEPAS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178030-A1 | TRPM8 AGONISTS AS COOLING AGENTS AND FOR THE TREATMENT OF DISEASE | Concentric Analgesics, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |
| US-20060287378-A1 | Novel pyrroles and imidazoles | WARNER-LAMBERT COMPANY LLC | 2006-12-21 | — | — | US | disclosed |
| US-20050239857-A1 | Novel imidazoles | BOLTON GARY L | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287378-A1 | Novel pyrroles and imidazoles | PPIP5K2, PPIE, PPOX | HRH3 2985/4885HIF1A 3484/4885EPAS1 1232/4885 |
| US-20050239857-A1 | Novel imidazoles | HMGCR, HMGB2, HMGB3 | HRH3 1190/4885HIF1A 3354/4885EPAS1 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.