Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26012913 | 0.77 | ESR1 (0.37) | ALDH1A1HSD17B10MAPK1TP53TSHR | |
| SCHEMBL22648624 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAPK1TP53TSHR | |
| SCHEMBL10394834 | 0.75 | RAPGEF4 (0.50) | ALDH1A1MAPK1TP53MEN1MAPT | |
| SCHEMBL12525500 | 0.72 | NOX1 (0.49) | ALDH1A1MAPK1MEN1MAPTKMT2A | |
| SCHEMBL18937422 | 0.72 | MAPT (0.50) | ALDH1A1HSD17B10TSHRKDM4EMEN1 | |
| SCHEMBL23347478 | 0.70 | CSNK1D (0.39) | ALDH1A1HSD17B10MAPK1TSHRKDM4E | |
| SCHEMBL1031031 | 0.70 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRKDM4E | |
| SCHEMBL8935677 | 0.69 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAPK1TP53TSHR | |
| SCHEMBL21323167 | 0.69 | RAPGEF4 (0.37) | ALDH1A1MAPK1MEN1LMNAMAPT | |
| SCHEMBL21565742 | 0.69 | LMNA (0.42) | ALDH1A1MAPK1HIF1AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4063377-A1 | MODIFICATION OF TRNA T-STEM FOR ENHANCING N-METHYL AMINO ACID INCORPORATION | The University of Tokyo (JP) | 2022-09-28 | — | — | EP | disclosed |