Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9267954 | 1.00 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Potassium Ion SCHEMBL29695336 | 1.00 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Potassium Ion SCHEMBL8047349 | 1.00 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Potassium Ion SCHEMBL28359445 | 1.00 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29218392 | 0.98 | LMNA (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27629349 | 0.98 | LMNA (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5917219 | 0.98 | LMNA (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10437942 | 0.98 | LMNA (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4802998 | 0.98 | LMNA (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Potassium Ion SCHEMBL10437946 | 0.98 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023013691-A1 | METHOD FOR PRODUCING ANTIBACTERIAL/ANTIVIRAL TEXTILE PRODUCT | 日華化学株式会社 | 2023-02-09 | — | — | WO | disclosed |
| US-8647741-B2 | Polypropylene fiber, method of producing the same and utilization of the same | KURARAY CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2130954-B1 | POLYPROPYLENE FIBER, METHOD OF PRODUCING THE SAME AND UTILIZATION OF THE SAME | KURARAY CO (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-20100173547-A1 | POLYPROPYLENE FIBER, METHOD OF PRODUCING THE SAME AND UTILIZATION OF THE SAME | KURARAY CO., LTD. (JP) | 2010-07-08 | — | — | US | disclosed |
| EP-2130954-A1 | POLYPROPYLENE FIBER, METHOD OF PRODUCING THE SAME AND UTILIZATION OF THE SAME | Kuraray Co., Ltd. (JP) | 2009-12-09 | — | — | EP | disclosed |