SCHEMBL24686234

SCHEMBL24686234

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5ccc6nccnc6c5)cc4)cc(-c4ccc(-c5ccc6nccnc6c5)cc4)c3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.50
PIK3CA P42336 2/20 0.49
ALK Q9UM73 1/20 0.47
GSK3B P49841 2/20 0.45
FLT3 P36888 1/20 0.45
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
MAP4K4 O95819 1/20 0.44
CCNB2 O95067 2/20 0.43
CDK1 P06493 2/20 0.43
CCNB1 P14635 2/20 0.43
CDK5 Q00535 2/20 0.43
CDK5R1 Q15078 2/20 0.43
CCNB3 Q8WWL7 2/20 0.43
GSK3A P49840 1/20 0.43
BACE1 P56817 1/20 0.43
PIK3CD O00329 1/20 0.43
PIK3R1 P27986 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27906803 0.96 TGFBR1 (0.53) TGFBR1PIK3CAALKGSK3BFLT3
SCHEMBL24686897 0.85 TGFBR1 (0.46) TGFBR1PIK3CAALKGSK3BFLT3
SCHEMBL8337311 0.84 NPC1 (0.52) TGFBR1GSK3BFLT3NPC1POLB
SCHEMBL24686673 0.82 MEN1 (0.54) TGFBR1GSK3BFLT3PIK3CDALDH1A1
SCHEMBL27996852 0.82 TGFBR1 (0.49) TGFBR1PIK3CAALKGSK3BFLT3
Biphenyl SCHEMBL3096874 0.79 ALDH1A1 (0.53) TGFBR1PIK3CAGSK3BNPC1RAB9A
SCHEMBL3390623 0.78 ALK (0.55) TGFBR1ALKGSK3BALDH1A1MAPT
SCHEMBL17231475 0.78 NPC1 (0.44) TGFBR1PIK3CAALKGSK3BFLT3
SCHEMBL17231465 0.78 NPC1 (0.44) TGFBR1PIK3CAALKGSK3BFLT3
SCHEMBL17231466 0.78 NPC1 (0.44) TGFBR1PIK3CAALKGSK3BFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11469378-B2 Electroluminescent compound and electroluminescent device including the same LG DISPLAY CO., LTD. (KR) 2022-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11469378-B2 Electroluminescent compound and electroluminescent device including the same LEF1, CLCN2, PIEZO1 TGFBR1 2870/4885PIK3CA 4521/4885ALK 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.