SCHEMBL24686352

SCHEMBL24686352

CN(C)/C=N/S(=O)(=O)c1cc(N)ccc1COc1ccc(F)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.41
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
GAA P10253 2/20 0.35
ALDH1A1 P00352 1/20 0.35
PTPN1 P18031 2/20 0.35
LMNA P02545 1/20 0.35
GSK3B P49841 1/20 0.34
BACE1 P56817 1/20 0.34
MMP1 P03956 2/20 0.34
KMT2A Q03164 1/20 0.33
CACNA1C Q13936 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24686356 0.78 RORC (0.41) PTPN1GSK3BBACE1
SCHEMBL24686354 0.74 KCNJ5 (0.51) ALDH1A1LMNA
SCHEMBL24686355 0.72 GAA (0.49) GAAALDH1A1LMNAKMT2A
SCHEMBL14336403 0.71 GAA (0.42) GAAALDH1A1LMNA
SCHEMBL19551921 0.71 LMNA (0.44) CA1CA2GAAALDH1A1LMNA
SCHEMBL29718844 0.71 LMNA (0.44) CA1CA2GAAALDH1A1LMNA
SCHEMBL19551919 0.71 LMNA (0.44) CA1CA2GAAALDH1A1LMNA
SCHEMBL29782326 0.68 LMNA (0.35) GAALMNA
SCHEMBL28835699 0.68 LMNA (0.35) GAALMNA
SCHEMBL24686020 0.68 GAA (0.41) GAAALDH1A1PTPN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022161416-A1 AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2022-08-04 WO disclosed