SCHEMBL24691246

SCHEMBL24691246

Cc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)NNC=O)cc12

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TAS1R3 Q7RTX0 1/20 0.47
▸ TAS1R1 Q7RTX1 1/20 0.47
▸ CTSL P07711 6/20 0.47
▸ CTSS P25774 5/20 0.47
▸ CTSB P07858 4/20 0.47
▸ ANPEP P15144 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26230797 0.89 ALB (0.55) CTSLCTSSCTSB
SCHEMBL25837527 0.87 CTSL (0.62) TAS1R3TAS1R1CTSLCTSSCTSB
SCHEMBL30001307 0.83 TAS1R3 (0.53) TAS1R3TAS1R1CTSLCTSSCTSB
SCHEMBL25244521 0.77 MEN1 (0.61) TAS1R3TAS1R1CTSLCTSSCTSB
SCHEMBL25288556 0.77 MEN1 (0.61) TAS1R3TAS1R1CTSLCTSSCTSB
SCHEMBL24019963 0.76 MEN1 (0.55) TAS1R3TAS1R1
SCHEMBL25287270 0.73 TAS1R3 (0.70) TAS1R3TAS1R1CTSLCTSS
SCHEMBL25244832 0.73 TAS1R3 (0.70) TAS1R3TAS1R1CTSLCTSS
SCHEMBL24029390 0.73 MEN1 (0.62) TAS1R3TAS1R1CTSLCTSSCTSB
SCHEMBL30001311 0.73 CTSL (0.68) CTSLCTSSCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 — — US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 — — US disclosed
WO-2022256434-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2022-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 TAS1R3 1588/4885TAS1R1 1625/4885CTSL 4/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 TAS1R3 1588/4885TAS1R1 1625/4885CTSL 4/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 TAS1R3 1588/4885TAS1R1 1625/4885CTSL 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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