Sugi Predict

Sugi Predict / Compounds / SCHEMBL933232

SCHEMBL933232

SCHEMBL933232

Cc1cn([C@@H]2O[C@H](C(O)O[PH](=O)OC3(O)C(O)[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3CO)C(O)C2O)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ ALB P02768 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ ADRA1A P35348 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ TK2 O00142 2/20 0.41
▸ TYMP P19971 4/20 0.37
▸ PYGM P11217 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65561 0.83 ALDH1A1 (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL932885 0.81 ALDH1A1 (0.40) ALDH1A1LMNAALBPOLBADRA1A
Ammonia Solution, Strong SCHEMBL2469221 0.81 ALDH1A1 (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL933748 0.75 TK2 (0.38) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL8422445 0.74 LMNA (0.52) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL8422441 0.74 LMNA (0.52) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL15164434 0.73 LMNA (0.50) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL933231 0.73 TK1 (0.47) —
SCHEMBL933229 0.73 TK1 (0.47) —
SCHEMBL11404005 0.72 DNPH1 (0.45) ALDH1A1LMNAALBPOLBADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2451461-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF Ontorii, Inc (US) 2012-05-16 — — EP disclosed
WO-2011005761-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS USE THEREOF ONTORII, INC (US) 2011-01-13 — — WO disclosed