Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28323158 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL30892365 | 0.68 | CA1 (0.40) | — | |
| SCHEMBL24697157 | 0.67 | AKT2 (0.39) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL1278347 | 0.65 | NR4A2 (0.56) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL18152025 | 0.62 | PTGS2 (0.45) | ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL27961010 | 0.60 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL20354759 | 0.60 | GPR84 (0.48) | ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL13800150 | 0.59 | CES2 (0.39) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22134820 | 0.59 | MGLL (0.33) | — | |
| SCHEMBL14700976 | 0.59 | MEN1 (0.32) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022254027-A1 | 3-PYRROLYLSULFONAMIDE COMPOUNDS AS GPR17 ANTAGONISTS | REWIND THERAPEUTICS NV (BE) | 2022-12-08 | — | — | WO | disclosed |