Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698793 | 0.88 | CASP1 (0.43) | PRMT6ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL24698115 | 0.88 | HRH2 (0.41) | ALDH1A1L3MBTL1LMNASMN1; SMN2KDM4E | |
| SCHEMBL24699446 | 0.87 | CASP1 (0.45) | PRMT6ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL24698174 | 0.86 | CFD (0.35) | PRMT6VCPCFDAOC3 | |
| SCHEMBL24698505 | 0.86 | CFD (0.37) | PRMT6ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL24697805 | 0.86 | CASP1 (0.44) | PRMT6ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL24698819 | 0.85 | PRMT6 (0.44) | PRMT6ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL24698186 | 0.85 | AOC3 (0.40) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL24698727 | 0.85 | TP53 (0.38) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL24697555 | 0.84 | PIK3CA (0.49) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |