Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24699042 | 0.86 | CYP11B2 (0.48) | CYP11B2KDM4EADORA2A | |
| SCHEMBL24698160 | 0.84 | AR (0.36) | CYP11B2KDM4EEGLN2ALDH1A1HPGD | |
| SCHEMBL30016865 | 0.84 | AR (0.36) | CYP11B2KDM4EEGLN2ALDH1A1HPGD | |
| SCHEMBL24699497 | 0.83 | HSD17B10 (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL24699459 | 0.79 | GBA1 (0.39) | KDM4EIGF1RALDH1A1MAPTHPGD | |
| SCHEMBL24699158 | 0.78 | IGF1R (0.34) | KDM4EIGF1RALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24697795 | 0.75 | ALDH1A1 (0.40) | KDM4EIGF1RALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24699477 | 0.75 | ALDH1A1 (0.47) | KDM4EIGF1RALDH1A1MAPTHPGD | |
| SCHEMBL24698171 | 0.74 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL24697814 | 0.74 | HRH3 (0.44) | ALDH1A1SMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |