SCHEMBL24699746

SCHEMBL24699746

c1ccc2cc(-n3c4ccc5ccccc5c4c4c5ccccc5c5[nH]c6ccccc6c5c43)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
CDK4 P11802 8/20 0.41
CCND1 P24385 8/20 0.41
CCNE2 O96020 3/20 0.41
CCNE1 P24864 3/20 0.41
CDK2 P24941 3/20 0.41
PRKCA P17252 3/20 0.41
GSK3B P49841 2/20 0.41
CCNB2 O95067 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
CDK1 P06493 1/20 0.41
CCNB1 P14635 1/20 0.41
MAP3K9 P80192 1/20 0.41
MAP3K11 Q16584 1/20 0.41
CCNB3 Q8WWL7 1/20 0.41
DYRK1A Q13627 2/20 0.38
CLK1 P49759 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19850015 0.89 KIF11 (0.44) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL23309130 0.88 KIF11 (0.41) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL20865400 0.87 KIF11 (0.39) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL20311942 0.83 GABRP (0.40) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL17451751 0.83 GABRP (0.42) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL17445432 0.82 GABRP (0.40) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL18667655 0.81 PMM2 (0.39) HTR5APMM2MPIPHOSPHO1
SCHEMBL21854006 0.79 KIF11 (0.48) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL19784803 0.79 KIF11 (0.44) KIF11CDK4CCND1CCNE2CCNE1
SCHEMBL22187577 0.79 PMM2 (0.36) HTR5APMM2MPIPHOSPHO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, TERT, VDAC2 KIF11 1440/4885CDK4 2675/4885CCND1 2272/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 KIF11 2478/4885CDK4 3286/4885CCND1 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.