Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904125 | 0.78 | PDE10A (0.40) | — | |
| SCHEMBL15904001 | 0.77 | PDE10A (0.41) | — | |
| SCHEMBL24701332 | 0.73 | CA1 (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL24701511 | 0.72 | HSP90AA1 (0.37) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL12854738 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL15904144 | 0.65 | PGK1 (0.33) | — | |
| SCHEMBL15904221 | 0.64 | NOS3 (0.31) | — | |
| SCHEMBL3739611 | 0.62 | NLRP3 (0.36) | — | |
| SCHEMBL19917127 | 0.62 | — | — | |
| SCHEMBL23187530 | 0.61 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752506-B1 | PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS | UNIV LIEGE (BE) | 2022-12-14 | — | — | EP | disclosed |