SCHEMBL18729486

SCHEMBL18729486

Cc1cnc(-c2ccccc2)cc1C1CCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.45
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
PDGFRB P09619 1/20 0.41
KDR P35968 1/20 0.41
FLT3 P36888 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALOX5AP P20292 2/20 0.40
FEN1 P39748 2/20 0.40
ADORA1 P30542 3/20 0.39
ADORA3 P0DMS8 2/20 0.39
ADORA2B P29275 2/20 0.39
LNPEP Q9UIQ6 1/20 0.39
ADORA2A P29274 2/20 0.38
PIM1 P11309 1/20 0.38
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CAMKK1 Q8N5S9 1/20 0.37
CAMKK2 Q96RR4 1/20 0.37
GABRA1 P14867 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22134625 0.90 ALOX5AP (0.39) LDHAALOX5APFEN1CAMKK1CAMKK2
SCHEMBL18729485 0.88 LDHA (0.49) LDHANPC1RAB9APDGFRBKDR
SCHEMBL24104666 0.87 ADORA3 (0.40) LDHANPC1RAB9AALOX5APFEN1
SCHEMBL24701784 0.86 LDHA (0.48) LDHANPC1RAB9APDGFRBKDR
SCHEMBL25984574 0.86 ADORA3 (0.37) LDHANPC1RAB9ASMN1; SMN2ALOX5AP
SCHEMBL22134627 0.84 S1PR1 (0.39) KDRALOX5APFEN1ADORA1ADORA3
SCHEMBL26312977 0.83 FEN1 (0.38) SMN1; SMN2ALOX5APFEN1ADORA1ADORA2A
SCHEMBL26310834 0.83 CYP1A2 (0.41) ALOX5APFEN1LNPEPMAPTHSD17B10
SCHEMBL18073581 0.82 ALOX5AP (0.39) LDHANPC1RAB9AALOX5APFEN1
SCHEMBL24104183 0.81 S1PR1 (0.41) ALOX5APFEN1CAMKK1CAMKK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11825734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11760770-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11765966-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11753427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-31 US disclosed
US-11744141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11139443-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-05 US disclosed
US-11114624-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-09-07 US disclosed
US-20200347085-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2020-11-05 US disclosed
US-20190252627-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
US-20190252619-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
US-20190088887-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-21 US disclosed
US-10236456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-03-19 US disclosed
US-20170294597-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-10-12 US disclosed
EP-3159350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-04-26 EP disclosed
EP-3001480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2017-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11114624-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND LDHA 727/4885NPC1 1777/4885RAB9A 2598/4885
US-20190088887-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR LDHA 1004/4885NPC1 4206/4885RAB9A 2009/4885
US-11825734-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP LDHA 975/4885NPC1 467/4885RAB9A 1234/4885
US-20200347085-A1 Organic electroluminescent materials and devices SSB, ADORA3, SNRPA1 LDHA 1205/4885NPC1 4193/4885RAB9A 1626/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR LDHA 1004/4885NPC1 4206/4885RAB9A 2009/4885
US-20190252627-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM LDHA 13/4885NPC1 2452/4885RAB9A 2539/4885
US-11139443-B2 Organic electroluminescent materials and devices ICOSLG, ORC3, OR10J3 LDHA 1654/4885NPC1 3005/4885RAB9A 1771/4885
US-11760770-B2 Organic electroluminescent materials and devices LEF1, L1CAM, AP1M1 LDHA 460/4885NPC1 3509/4885RAB9A 430/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 LDHA 192/4885NPC1 228/4885RAB9A 2081/4885
US-11753427-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 LDHA 150/4885NPC1 171/4885RAB9A 991/4885
US-10236456-B2 Organic electroluminescent materials and devices ADORA1, ADORA3, M6PR LDHA 885/4885NPC1 4383/4885RAB9A 450/4885
US-11744141-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, LBR LDHA 144/4885NPC1 3169/4885RAB9A 2560/4885
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, PORCN LDHA 751/4885NPC1 2010/4885RAB9A 2076/4885
US-20170294597-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ADORA1, ADORA3, M6PR LDHA 885/4885NPC1 4383/4885RAB9A 450/4885
US-11765966-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, EPM2A LDHA 14/4885NPC1 3768/4885RAB9A 1580/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR LDHA 1004/4885NPC1 4206/4885RAB9A 2009/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP LDHA 318/4885NPC1 453/4885RAB9A 1636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.