SCHEMBL24701727

SCHEMBL24701727

Ic1csc2c1CCCC2

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.41
ALDH1A1 P00352 5/20 0.40
LMNA P02545 3/20 0.40
GFER P55789 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTT P42858 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 8/20 0.38
NPC1 O15118 3/20 0.38
POLB P06746 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
STAT3 P40763 1/20 0.38
MAPT P10636 4/20 0.36
TP53 P04637 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13021599 0.73 HPGD (0.44) HPGDALDH1A1LMNAGFERTDP1
SCHEMBL2039293 0.73 HPGD (0.42) HPGDALDH1A1LMNAGFERTDP1
SCHEMBL23840301 0.71 HPGD (0.44) HPGDALDH1A1LMNAGFERTDP1
SCHEMBL16297464 0.68
SCHEMBL15920403 0.68 BPTF (0.41) HPGDALDH1A1LMNAGFERTDP1
SCHEMBL24733006 0.67 MAOA (0.38) HPGDALDH1A1RAB9AMEN1KMT2A
SCHEMBL15073114 0.67 HPGD (0.47) HPGDALDH1A1HTTL3MBTL1SMN1; SMN2
SCHEMBL18430366 0.67 ALDH1A1 (0.43) HPGDALDH1A1LMNAGFERTDP1
SCHEMBL5786181 0.67 HPGD (0.41) HPGDALDH1A1LMNAGFERTDP1
SCHEMBL1121587 0.67 HPGD (0.41) HPGDALDH1A1LMNAGFERTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 HPGD 3585/4885ALDH1A1 307/4885LMNA 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.