SCHEMBL24701900

SCHEMBL24701900

Cc1ccc2c(c1)C(C)(C)N(C)C2(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MAPT P10636 4/20 0.37
MEN1 O00255 3/20 0.37
HTT P42858 3/20 0.37
KDM4E B2RXH2 3/20 0.37
TDP1 Q9NUW8 3/20 0.36
THRB P10828 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
LMNA P02545 1/20 0.34
RECQL P46063 1/20 0.34
AKR1B1 P15121 2/20 0.33
PKM P14618 1/20 0.33
CNR1 P21554 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18620881 0.82 LMNA (0.38) KMT2AMAPTMEN1HTTKDM4E
SCHEMBL15614854 0.76 AKR1B1 (0.35) KMT2AMAPTMEN1TP53SMN1; SMN2
SCHEMBL24701904 0.74 KMT2A (0.33) KMT2AMAPTMEN1HTTKDM4E
SCHEMBL24701908 0.74 KMT2A (0.33) KMT2AMAPTMEN1HTTKDM4E
SCHEMBL12017193 0.72 ALDH1A1 (0.38) KMT2AMAPTMEN1KDM4ETDP1
SCHEMBL679133 0.72 KMT2A (0.38) KMT2AMAPTMEN1HTTKDM4E
SCHEMBL30530260 0.70 TDP1 (0.42) KMT2AMAPTMEN1HTTKDM4E
SCHEMBL15679423 0.70 THRB (0.37) KMT2AMAPTMEN1HTTKDM4E
SCHEMBL15427862 0.69 PTK2 (0.42) KMT2AMEN1TDP1THRBTP53
SCHEMBL20618318 0.68 SLC6A2 (0.35) KMT2AMAPTMEN1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 KMT2A 2084/4885MAPT 2059/4885MEN1 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.