SCHEMBL24704607

SCHEMBL24704607

CCCCCCCC(CCCCCC)NC(CCC)CCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.46
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
EPHX1 P07099 1/20 0.40
PLA2G2C Q5R387 2/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
CA2 P00918 1/20 0.39
OPRM1 P35372 1/20 0.39
FDPS P14324 3/20 0.37
GPR84 Q9NQS5 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22646175 1.00 DNM1 (0.46) DNM1LMNATSHRTHRBEPHX1
SCHEMBL277799 0.97 LMNA (0.42) DNM1LMNATSHRTHRBEPHX1
SCHEMBL9818090 0.97 LMNA (0.42) DNM1LMNATSHRTHRBEPHX1
SCHEMBL13851797 0.92 TSHR (0.47) DNM1LMNATSHRTHRBEPHX1
SCHEMBL5692575 0.92 TSHR (0.47) DNM1LMNATSHRTHRBEPHX1
SCHEMBL1678737 0.92 DNM1 (0.46) DNM1LMNATSHRTHRBEPHX1
SCHEMBL12479364 0.92 TSHR (0.47) DNM1LMNATSHRTHRBEPHX1
SCHEMBL11681882 0.92 TSHR (0.47) DNM1LMNATSHRTHRBEPHX1
SCHEMBL11701212 0.92 TSHR (0.47) DNM1LMNATSHRTHRBEPHX1
SCHEMBL20054095 0.92 TSHR (0.47) DNM1LMNATSHRTHRBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524943-B1 Benzocarbonyl compounds VIVACE THERAPEUTICS, INC. (US) 2022-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524943-B1 Benzocarbonyl compounds YAP1, TEAD2, TEAD3 DNM1 286/4885LMNA 1755/4885TSHR 3038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.