Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 5/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24712995 | 0.74 | PRCP (0.50) | CYP3A4PRCP | |
| SCHEMBL24712998 | 0.69 | PRCP (0.42) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24712806 | 0.66 | CD44 (0.41) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL24712996 | 0.65 | GSTP1 (0.37) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL24712922 | 0.62 | MEN1 (0.33) | MEN1KMT2APRCP | |
| SCHEMBL31441037 | 0.62 | PNMT (0.45) | MAPTKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL8678488 | 0.62 | PNMT (0.45) | MAPTKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL24628686 | 0.61 | DRD2 (0.39) | GRM5PNMTPRCP | |
| SCHEMBL30775283 | 0.59 | GRM5 (0.54) | MAPTKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL5871989 | 0.58 | APP (0.75) | MAPTKDM4EMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218391-A1 | CHIRAL SPIRO AMMONIUM SALT COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 西湖大学 | 2022-10-20 | — | — | WO | disclosed |