Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30735881 | 0.86 | SIGMAR1 (0.33) | — | |
| SCHEMBL30735679 | 0.78 | SIGMAR1 (0.33) | — | |
| SCHEMBL30735764 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL30735672 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL30735767 | 0.75 | KIF11 (0.40) | — | |
| SCHEMBL30735913 | 0.75 | CYP3A4 (0.42) | APPOPRM1 | |
| SCHEMBL30735516 | 0.74 | ESR1 (0.40) | — | |
| SCHEMBL10154118 | 0.68 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL22184049 | 0.62 | CYP11B1 (0.39) | RXRARXRB | |
| SCHEMBL14515033 | 0.62 | ALDH1A1 (0.41) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430636-A | Chiral spiro phosphoramide compound and preparation method and application thereof | 南开大学 | 2024-01-23 | — | — | CN | disclosed |