Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806911 | 0.81 | KEAP1 (0.47) | PIN1CTSGITGB3ITGB1ITGAV | |
| SCHEMBL19806987 | 0.81 | PIN1 (0.51) | PIN1KDM4ACACNA1BCTSGITGB3 | |
| SCHEMBL19806913 | 0.80 | KEAP1 (0.47) | PIN1CTSGITGB3ITGB1ITGAV | |
| SCHEMBL19807066 | 0.79 | PIN1 (0.49) | PIN1CTSGITGB3ITGB1ITGAV | |
| SCHEMBL24713050 | 0.78 | SSTR2 (0.53) | PIN1KDM4ACACNA1BCTSGITGB3 | |
| SCHEMBL22085206 | 0.77 | KDM1A (0.50) | PIN1KDM4ACACNA1BCTSGITGB3 | |
| Cyclorgdfv SCHEMBL29973120 | 0.77 | ITGB3 (0.58) | KDM4ACTSGITGB3ITGB1ITGAV | |
| Cyclorgdfv SCHEMBL25474158 | 0.77 | ITGB3 (0.58) | KDM4ACTSGITGB3ITGB1ITGAV | |
| Cyclorgdfv SCHEMBL19605549 | 0.77 | ITGB3 (0.58) | KDM4ACTSGITGB3ITGB1ITGAV | |
| Cyclorgdfv SCHEMBL19605449 | 0.77 | ITGB3 (0.58) | KDM4ACTSGITGB3ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387608-A1 | ADRENOMEDULLIN-ANALOGUES FOR LONG-TERM STABILIZATION AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387608-A1 | ADRENOMEDULLIN-ANALOGUES FOR LONG-TERM STABILIZATION AND THEIR USE | VEGFA, ADM2, SERPINA6 | PIN1 879/4885KDM4A 4876/4885CACNA1B 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.