Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 5/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806911 | 0.99 | KEAP1 (0.47) | KEAP1PLAUCTSGALBPLK1 | |
| SCHEMBL19807007 | 0.92 | CTSG (0.50) | PLAUCTSGALBSSTR1SSTR2 | |
| SCHEMBL24713350 | 0.80 | PIN1 (0.53) | KEAP1PLAUCTSGSIRT2SIRT1 | |
| SCHEMBL19806987 | 0.78 | PIN1 (0.51) | KEAP1PLAUCTSGSSTR1SSTR2 | |
| SCHEMBL24713050 | 0.76 | SSTR2 (0.53) | KEAP1PLAUCTSGSSTR1SSTR2 | |
| SCHEMBL19807066 | 0.76 | PIN1 (0.49) | PLAUCTSGSSTR1SSTR2SSTR4 | |
| SCHEMBL8365140 | 0.72 | ITGB3 (0.47) | KEAP1PLAUCTSGNFE2L2KLKB1 | |
| SCHEMBL7743670 | 0.72 | ITGB3 (0.56) | CTSGITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL7744260 | 0.72 | ITGB3 (0.56) | CTSGITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL22970321 | 0.72 | ITGB3 (0.56) | CTSGITGB3ITGB1ITGAVITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022780-A1 | STABILIZATION ADRENOMEDULLIN DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022780-A1 | STABILIZATION ADRENOMEDULLIN DERIVATIVES AND USE THEREOF | ADM2, SERPINA6, SERPINC1 | KEAP1 278/4885PLAU 198/4885CTSG 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.