Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387862 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CA1CA2CA9ALPL | |
| SCHEMBL23282 | 0.79 | CA1 (0.39) | ALDH1A1CA1CA2CA9ALPL | |
| SCHEMBL15066542 | 0.78 | CYP1A2 (0.32) | ALDH1A1ALPLCYP1A2TSHRHSD17B10 | |
| SCHEMBL15066836 | 0.74 | — | — | |
| SCHEMBL157754 | 0.74 | — | — | |
| SCHEMBL15066773 | 0.74 | CA1 (0.35) | ALDH1A1CA1CA2CA9ALPL | |
| SCHEMBL28822186 | 0.74 | ALPL (0.35) | TRPV4CA1CA2CA9ALPL | |
| SCHEMBL29185167 | 0.72 | ABCB11 (0.33) | TRPV4 | |
| SCHEMBL15067928 | 0.72 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL15067220 | 0.72 | CA1 (0.37) | ALDH1A1CA1CA2CA9PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | claimed |
| US-9006266-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | claimed |
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | disclosed |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-2921485-B1 | ISOXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2921484-B1 | OXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2609094-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | US | disclosed |
| US-9930890-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-04-03 | — | — | US | disclosed |
| EP-2921495-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-20180007903-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-01-11 | — | — | US | disclosed |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-22 | — | — | US | disclosed |
| EP-2797899-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-07-24 | — | — | US | disclosed |
| US-8759527-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-24 | — | — | US | disclosed |
| US-20130296272-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
| WO-2013098229-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2609094-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2012025557-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | RB1, RBX1, RRP12 | ALDH1A1 1534/4885TRPV4 4187/4885CA1 3213/4885 |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | ALDH1A1 1534/4885TRPV4 4187/4885CA1 3213/4885 |
| US-20180007903-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | ALDH1A1 1292/4885TRPV4 3665/4885CA1 3347/4885 |
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | ALDH1A1 1292/4885TRPV4 3665/4885CA1 3347/4885 |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | ALDH1A1 1608/4885TRPV4 4360/4885CA1 3427/4885 |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | ALDH1A1 1292/4885TRPV4 3665/4885CA1 3347/4885 |
| US-20130296272-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, CYP1A2 | ALDH1A1 1292/4885TRPV4 3665/4885CA1 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.