Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140385 | 0.83 | HSP90AA1 (0.41) | MMP2NPC1RAB9AL3MBTL1GAA | |
| SCHEMBL7191141 | 0.79 | MMP2 (0.34) | MMP2NPC1RAB9AL3MBTL1ALOX15 | |
| SCHEMBL8520219 | 0.76 | L3MBTL1 (0.44) | MMP2NPC1RAB9AL3MBTL1GAA | |
| SCHEMBL3078969 | 0.76 | LMNA (0.52) | MMP2NPC1RAB9AL3MBTL1GAA | |
| SCHEMBL143318 | 0.75 | — | — | |
| SCHEMBL6558400 | 0.74 | GAA (0.42) | MMP2NPC1RAB9AL3MBTL1GAA | |
| SCHEMBL1172644 | 0.74 | — | — | |
| SCHEMBL16511527 | 0.74 | MMP2 (0.44) | MMP2NPC1RAB9AL3MBTL1GAA | |
| SCHEMBL22060026 | 0.73 | JAK2 (0.47) | NPC1RAB9AL3MBTL1GAATSHR | |
| SCHEMBL7991021 | 0.73 | G6PD (0.47) | MMP2NPC1RAB9AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |
| CN-102077060-B | Monitoring system based on corrosion metal | G. PATEL (US) | 2014-10-29 | — | — | CN | disclosed |
| CN-102077060-A | Monitoring system based on corrosion metal | PATEL G | 2011-05-25 | — | — | CN | disclosed |