Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511754 | 0.85 | ALDH1A1 (0.43) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL12123913 | 0.82 | HSP90AA1 (0.42) | ALDH1A1CYP3A4HSP90AA1MAPTKMT2A | |
| SCHEMBL8520219 | 0.78 | L3MBTL1 (0.44) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL143318 | 0.77 | — | — | |
| SCHEMBL24716112 | 0.74 | MMP2 (0.47) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL2214991 | 0.74 | ALDH1A1 (0.59) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL18880528 | 0.74 | TSHR (0.48) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL8168365 | 0.74 | CD44 (0.50) | ALDH1A1CYP3A4TSHRHPGDHSD17B10 | |
| SCHEMBL22060026 | 0.74 | JAK2 (0.47) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL24052991 | 0.74 | CYP3A4 (0.35) | GAAL3MBTL1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107151356-A | The composition for thermoplastic elastomer being made up of elastomer, non-elastomeric polyolefin and polyolefin block copolymer analog thermoplastic elastomer | 克赖布尔格TPE有限责任两合公司 | 2017-09-12 | — | — | CN | disclosed |
| US-8063053-B2 | 1-(arylsulfonyl)-4-(piperazin-1-yl)-1H-benzimidazoles as 5-hydroxytryptamine-6 ligands | WYETH LLC (US) | 2011-11-22 | — | — | US | disclosed |
| CN-101563786-B | Electronic device module comprising polyolefin copolymer | DOW GLOBAL TECHNOLOGIES INC | 2011-08-17 | — | — | CN | disclosed |
| CN-101517750-B | Electronic device module comprising ethylene multi-block copolymer | DOW GLOBAL TECHNOLOGIES INC | 2011-06-29 | — | — | CN | disclosed |
| US-20100120779-A1 | 1-(ARYLSULFONYL)-4-(PIPERAZIN-1-YL)-1H-BENZIMIDAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2010-05-13 | — | — | US | disclosed |
| CN-101675099-A | Isocyanate, diisocyanate and (meth) acrylate compounds for minimizing scorch and diisocyanate compounds for promoting cure in crosslinkable compositions | OW GLOBAL TECHNOLOGIES INC | 2010-03-17 | — | — | CN | disclosed |
| CN-101563786-A | Electronic device module comprising polyolefin copolymer | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-10-21 | — | — | CN | disclosed |
| CN-101517750-A | Electronic device module comprising ethylene multi-block copolymer | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-08-26 | — | — | CN | disclosed |
| EP-1395241-A1 | IMPLANTABLE MEDICAL DEVICE WITH CONTROLLABLE GASEOUS AGENT RELEASE SYSTEM | Medtronic, Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002096387-A1 | IMPLANTABLE MEDICAL DEVICE WITH CONTROLLABLE GASEOUS AGENT RELEASE SYSTEM | MEDTRONIC, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120779-A1 | 1-(ARYLSULFONYL)-4-(PIPERAZIN-1-YL)-1H-BENZIMIDAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | HTR6, TPH1, HTR4 | GAA 3973/4885L3MBTL1 4278/4885NPC1 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.