SCHEMBL24717175

SCHEMBL24717175

CCCCSc1ccc(C#Cc2ccc(O)c(F)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.40
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MGLL Q99685 6/20 0.36
FAAH O00519 2/20 0.34
CNR1 P21554 2/20 0.34
XDH P47989 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
SHBG P04278 1/20 0.33
DGAT1 O75907 1/20 0.33
PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24296712 0.79 AR (0.42) ARMAOAMAOBXDHKDM4E
SCHEMBL19057531 0.78 AR (0.36) ARMAOAMAOBXDHKDM4E
SCHEMBL24296674 0.77 AR (0.42) ARMAOAMAOBXDHKDM4E
SCHEMBL24717167 0.77 XDH (0.37) ARMAOAMAOBXDHKDM4E
SCHEMBL19057286 0.76 AR (0.36) ARMAOAMAOBXDHKDM4E
SCHEMBL10300068 0.75 THRB (0.48) ARMAOAMAOBKDM4ENPC1
SCHEMBL17089264 0.75 MAOA (0.49) ARMAOAMAOBXDHKDM4E
SCHEMBL7710176 0.74 HNF4A (0.42) MGLLKDM4ESHBGFFAR1FFAR4
SCHEMBL23335180 0.74 KDM4E (0.53) ARMAOAMAOBMGLLKDM4E
SCHEMBL29306195 0.74 AR (0.40) ARMAOAMAOBFAAHXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
WO-2022234709-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE AND ANTENNA EACH USING SAME DIC株式会社 2022-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME TTI2, CCT4, CCT2 AR 1563/4885MAOA 4491/4885MAOB 4469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.